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Thursday, June 30, 2022

U.S. Will Now Offer Vaccinations Against Monkeypox to Anyone Who May Have Been Exposed to the Virus - Yahoo Entertainment

NYC launches monkeypox vaccination site
NYC launches monkeypox vaccination site

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As monkeypox cases rise across the country, U.S. health officials plan to expand access to vaccinations against the virus.

On Tuesday, the Department of Health and Human Services announced vaccinations will now be available to anyone with presumed exposure to the virus, in addition to individuals with known exposure who were already being offered immunizations.

"Within days of the first confirmed case of monkeypox in the United States, we quickly began deploying vaccines and treatment to help protect the American public and limit the spread of the virus," said HHS Secretary Xavier Becerra.

This 2003 electron microscope image made available by the Centers for Disease Control and Prevention shows mature, oval-shaped monkeypox virions, left, and spherical immature virions, right, obtained from a sample of human skin associated with the 2003 prairie dog outbreak. Monkeypox, a disease that rarely appears outside Africa, has been identified by European and American health authorities in recent days.
This 2003 electron microscope image made available by the Centers for Disease Control and Prevention shows mature, oval-shaped monkeypox virions, left, and spherical immature virions, right, obtained from a sample of human skin associated with the 2003 prairie dog outbreak. Monkeypox, a disease that rarely appears outside Africa, has been identified by European and American health authorities in recent days.

Cynthia S. Goldsmith, Russell Regner/CDC via AP Monkeypox virions

RELATED: What to Know About Monkeypox — Including How It Spreads — as the CDC Confirms a U.S. Case

He continued, "While monkeypox poses minimal risk to most Americans, we are doing everything we can to offer vaccines to those at high risk of contracting the virus. This new strategy allows us to maximize the supply of currently available vaccines and reach those who are most vulnerable to the current outbreak."

The department said it will release 56,000 doses of the Jynneos vaccine immediately, with an additional 240,000 doses being made available in the coming weeks. In total, 1.6 million doses of the vaccine are expected by the end of the year.

Vaccines will now be available to individuals "who had close physical contact with someone diagnosed with monkeypox, those who know their sexual partner was diagnosed with monkeypox, and men who have sex with men who have recently had multiple sex partners in a venue where there was known to be monkeypox or in an area where monkeypox is spreading," according to the department's press release.

The vaccine will be distributed using a four-tier strategy that prioritizes areas with the highest case rates of monkeypox. Within each tier, the allocation of doses will be determined by the number of individuals at risk for the virus who also have pre-existing conditions.

RELATED: CDC Confirms First U.S. Case of Monkeypox in 2022, Health Officials Assure 'No Risk' to Public

"We have vaccines and treatments to respond to the current monkeypox outbreak thanks to years of sustained investment and planning," HHS Assistant Secretary for Preparedness and Response Dawn O'Connell said in a statement.

She continued, "Our goal right now is to ensure that the limited supply of JYNNEOS vaccine is deployed to those who can benefit from it most immediately, as we continue to secure additional vaccine doses."

In addition to the Jynneos vaccine, ACAM2000 — a smallpox vaccine — is also being made available but it is known to have "significant side effects is not recommended for everyone," according the department.

RELATED: CDC Issues New Guidance on Monkeypox Symptoms as Cases Rise in the United States

But the new vaccination strategy was criticized by experts who believe that more immunization is needed.

"Many of us are concerned that the window is closing for us to be able to eliminate monkeypox," Dr. Celine Gounder, an infectious disease expert and editor at large for public health at Kaiser Health News, told The New York Times.

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"If we don't start vaccinating more quickly and broadly, we're going to have a very difficult time containing this," she added.

As of Wednesday, there are currently 305 confirmed monkeypox cases in the U.S., according to the Centers for Disease Control and Prevention's 2022 Monkeypox Outbreak Global Map.

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WHO warns 'sustained transmission' of monkeypox risks vulnerable groups - Fox News

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The World Health Organization says "sustained transmission" of monkeypox worldwide could see the virus begin to move into high-risk groups, such as pregnant women, immunocompromised people, and children.

WHO said on Wednesday it was investigating reports of infected children, including two cases in Britain, as well as following up reports in Spain and France. None of the cases in children have been severe.

The virus has now been identified in more than 50 new countries outside the countries in Africa where it is endemic. Cases are also rising in those countries, said WHO, calling for testing to be ramped up.

WHO SAYS MONKEYPOX RISK ASSESSED AS ‘MODERATE'

"I'm concerned about sustained transmission because it would suggest that the virus (is) establishing itself and it could move into high risk groups including children, the immunocompromised and pregnant women," said WHO chief Tedros Adhanom Ghebreyesus in an online briefing from Geneva on Wednesday.

A logo is pictured at the World Health Organization building in Geneva, Switzerland, on Feb. 2, 2020. 

A logo is pictured at the World Health Organization building in Geneva, Switzerland, on Feb. 2, 2020.  (Reuters/Denis Balibouse)

There have been more than 3,400 cases of monkeypox, and one death, since the outbreak began in May, largely in Europe among men who have sex with men, according to a WHO tally. There have also been more than 1,500 cases and 66 deaths in countries this year where it more usually spreads.

Last week, the WHO ruled that the outbreak did not yet represent a public health emergency, its highest level of alert. However, Tedros said the WHO was tracking the outbreak closely and would reconvene the committee "as soon as possible" to assess whether this was still the case. [L1N2YE0YM]

MONKEYPOX MUTATING MORE THAN PREVIOUSLY THOUGHT, RESEARCHERS SAY

The U.N. agency said it was also working on a mechanism to distribute vaccines more equitably, after countries including Britain and the United States suggested they were willing to share their stockpiled smallpox vaccines, which also protect against monkeypox.

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Wednesday, June 29, 2022

WHO monkeypox emergency committee to reconvene ‘as soon as possible’ due to ‘evolving situation’ - Fortune

WHO monkeypox emergency committee to reconvene due to 'evolving situation' | Fortune

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Monday, June 27, 2022

Thousands of Army National Guard soldiers who haven't gotten COVID-19 vaccine could be forced out - Fox News

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Up to 40,000 Army National Guard soldiers across the country – about 13% of the force – have not gotten the mandated COVID-19 vaccine, and as the deadline for shots looms, at least 14,000 of them have flatly refused and could be forced out of the service.

Guard soldiers have until Thursday to get the vaccine. According to data obtained by The Associated Press, between 20% to 30% of Guard members in six states are not vaccinated, and more than 10% in 43 other states still need shots.

Guard leaders say states are doing all they can to encourage soldiers to get vaccinated by the deadline. And they said they will work with the roughly 7,000 who have sought exemptions, which are almost all for religious reasons.

"We're going to give every soldier every opportunity to get vaccinated and continue their military career. Every soldier that is pending an exemption, we will continue to support them through their process," said Lt. Gen. Jon Jensen, director of the Army National Guard, in an Associated Press interview. "We're not giving up on anybody until the separation paperwork is signed and completed. There's still time."

ARMY NEARS 100% VACCINATION, CLAIMS ONLY 1% REFUSAL AMONG TROOPS

Mississippi Army National Guard Sgt. Chase Toussaint, right, and Staff Sgt. Matthew Riley, both with the Maneuver Area Training Equipment Site of Camp Shelby, fill 5-gallon buckets in March 2021 at a Jackson water distribution site. 

Mississippi Army National Guard Sgt. Chase Toussaint, right, and Staff Sgt. Matthew Riley, both with the Maneuver Area Training Equipment Site of Camp Shelby, fill 5-gallon buckets in March 2021 at a Jackson water distribution site.  (AP Photo/Rogelio V. Solis, File)

Defense Secretary Lloyd Austin last year ordered all service members – active duty, National Guard and Reserves – to get the vaccine, saying it is critical to maintaining the health and readiness of the force. The military services had varying deadlines for their forces, and the Army National Guard was given the longest amount of time to get the shots, mainly because it's a large force of about 330,000 soldiers who are scattered around the country, many in remote locations.

The Army Guard's vaccine percentage is the lowest among the U.S. military – with all the active-duty Army, Navy, Air Force and Marine Corps at 97% or greater and the Air Guard at about 94%. The Army reported Friday that 90% of Army Reservists were partially or completely vaccinated.

The Pentagon has said that after June 30, unvaccinated Guard members won't be paid by the federal government when they are activated on federal status, which includes their monthly drill weekends and their two-week annual training period. Guard troops mobilized on federal status and assigned to the southern border or on COVID-19 missions in various states also would have to be vaccinated or they would not be allowed to participate or be paid.

To make it more complicated, however, Guard soldiers on state activate duty may not have to be vaccinated – based on the requirements in their states. As long as they remain in state duty status, they can be paid by the state and used for state missions.

Ohio Gov. Mike DeWine and his wife Fran talk with specialist Emily Milosevic as they tour the Defense Supply Center in Columbus, Ohio, in January 2022.

Ohio Gov. Mike DeWine and his wife Fran talk with specialist Emily Milosevic as they tour the Defense Supply Center in Columbus, Ohio, in January 2022. (AP Photo/Paul Vernon, File)

At least seven governors formally asked Austin to reconsider or not enforce the vaccine mandate for National Guard members, and some filed or signed on to lawsuits. In letters to the governors, Austin declined, and said the coronavirus "takes our service members out of the fight, temporarily or permanently, and jeopardizes our ability to meet mission requirements." He said Guard troops must either get the vaccine or lose their Guard status.

Jensen and Maj. Gen. Jill Faris, director of the Guard's office of the Joint Surgeon General, said they are working with states' adjutants general to get progress updates, including on the nearly 20,000 troops who are not flat refusals and haven't submitted any type of exemption request. Some, they said, may just be a lag in self-reporting, while others may still be undecided.

"Part of those undefined are our soldiers who say, 'Well, I have until 30 June and so I'll take till 30 June,'" said Jensen.

Others may have promised to bring in vaccine paperwork, and haven't done it yet. Still others are on the books, but haven't yet reported to basic training, so don't have to be vaccinated until they get there. It's not clear how many are in each category.

Jensen acknowledged that if the current numbers hold, there are concerns about possible impact on Guard readiness in the states, including whether it will affect any units preparing to deploy.

DEFENSE DEPARTMENT REVERSES RULE, ALLOWS HIV POSITIVE MEMBERS TO SERVE

Army National Guard Staff Sgt. Andrew Bates pulls up tape marking a line at a coronavirus mass-vaccination site at the former Citizens Bank headquarters in Cranston, Rhode Island, on June 10, 2021.

Army National Guard Staff Sgt. Andrew Bates pulls up tape marking a line at a coronavirus mass-vaccination site at the former Citizens Bank headquarters in Cranston, Rhode Island, on June 10, 2021. (AP Photo/David Goldman)

"When you're looking at, 40,000 soldiers that potentially are in that unvaccinated category, absolutely there's readiness implications on that and concerns associated with that," said Jensen. "That's a significant chunk."

Overall, according to the data obtained by the AP, about 85% of all Army Guard soldiers are fully vaccinated. Officials said that if those with one shot are counted, 87% are at least partially vaccinated.

Across the country, in all but one case, Guard soldiers are vaccinated at a higher rate than the general population in their state. Only in New Jersey is the percentage of vaccinated Guard solders very slightly lower than the state's overall population, as of earlier this month when the data was collected.

The three U.S. territories – Virgin Islands, Guam and Puerto Rico – and the District of Columbia, all have more than 90% of their soldiers fully vaccinated. The highest percentage is in Hawaii, with nearly 97%, while the lowest is Oklahoma, at just under 70%.

Guard leaders in the states have run special shot programs, and provided as much information as possible to their forces in order to keep them on the job.

In Tennessee, they set up small teams in the east, west and central regions and did monthly events providing vaccines to troops who wanted them. And every Wednesday, Guard members could make appointments for shots in the middle Tennessee region, in Smyrna. In addition, in early June they called in all soldiers who have so far refused the vaccine.

"We held a big, mass event," said Army Guard Col. Keith Evans. "We had all of our medical providers here. So if there were any questions to clear up, any misconceptions, any misinformation, we had all of our data and were able to provide them all the information."

Evans, who is commander of his Army Guard's medical readiness command, said they also had recruiting and other leaders there who could explain what would happen if soldiers chose to not get the shot and ended up leaving the Guard.

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"We wanted to let them know what benefits they had earned because these are soldiers that had done their time, served their country," said Evans.

Officials say they believe the information campaign has been working. Jensen said about 1,500 soldiers a week around the country are moving into the vaccinated category. "We expect, as we approach the deadline, that we'll see some larger growth." 

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Monkeypox case found in Mecklenburg County - WRAL News

— The second case of monkeypox in North Carolina has been found in Mecklenburg County.

NBC affiliate WCNC reports this is the first confirmed case in the county, but county health leaders say there are likely other cases.

Last Thursday, the state Department of Health and Human Services said a case of the viral infection had been found in a North Carolina resident. While state health officials did not say where in North Carolina the case was found, the Haywood County health department confirmed a known case was there.

In both cases, county health leaders said the patients were isolating at home and people who were in close contact with the patients will be notified.

"It is very important to be aware of the symptoms of monkeypox and to be vigilant," said Mecklenburg County Public Health Director Dr. Raynard Washington. "Individuals with concerning rashes should contact their health care provider."

Washington also encouraged doctors to consider monkeypox in people who have a rash or skin lesion resembling the infection.

"Although monkeypox remains rare, the CDC is reporting that cases continue to rise across the country" he said.

Monkeypox is a rare but potentially serious, viral illness that involves flu-like symptoms swelling of the lymph nodes and a rash that includes bumps that are initially filled with fluid before scabbing over.

The virus does not spread easily, and can only spread through people who have had close contact. The most common way the infection is spread is when people come into close contact with the rash, scabs or bodily fluids of someone who has monkey pox. The infection can also spread through the air, but only to those very close, with face-to-face contact like kissing of snuggling.

There is no treatment specific to monkeypox, but because it is a virus, antiviral medications are often given to treat infections and to prevent them in people who may be exposed to the virus.

There is a vaccine to prevent monkeypox, but it is not used widely in the United States because historically the number of cases in the country has not been significant.

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Sunday, June 26, 2022

Experts expect subvariants to cause 'substantial' summer cases of COVID-19 - The Boston Globe

Until last week, Dr. Ali Mokdad expected the United States to have “a very good summer” in terms of COVID-19. Projections by the Institute for Health Metrics and Evaluation, where he works, forecasted falling cases, hospitalizations, and deaths through at least September.

Then, circumstances changed: Researchers discovered that BA.4 and BA.5 — subvariants of Omicron spreading in the United States — are “immune escapes,” adept at avoiding the antibodies the body produces after vaccination or infection to neutralize the virus.

“That has changed our view for what will happen this summer,” Mokdad said. Though he still expects cases to decrease, the decline will be slower and smaller than projected.

Dr. Dan Barouch, director of the Center for Virology and Vaccine Research at Beth Israel Deaconess Medical Center, said he anticipates the subvariants will spawn a summer of “substantial infections,” but low rates of hospitalization and death.

As of the week ending June 18, BA.4 and BA.5 accounted for about 35 percent of cases in the United States, according to estimates by the Centers for Disease Control and Prevention — figures that experts say should rise in the weeks to come.

“I expect that BA.5 will likely become the dominant virus in the United States this summer,” Barouch said.

Barouch published a study in the New England Journal of Medicine on Wednesday that found that BA.4 and BA.5 are far better at avoiding antibodies than any prior strains — three times better than BA.1 and BA.2, and 20 times better than the “original” COVID-19.

“What we’re seeing with each subsequent variant is iteratively higher levels of transmissibility and higher levels of antibody immune escape,” he said. As a result, “we’re seeing high levels of infection in populations that are highly vaccinated, as well as populations that have a high level of natural immunity to the prior variants.”

COVID vaccines work by prompting the body to produce an immune response, including antibodies, to fight the virus. As the subvariants start to avoid those antibodies, vaccination affords less and less protection against infection.

However, experts emphasize that vaccines remain very effective at preventing severe cases of COVID-19.

“If people have vaccine immunity or natural immunity, then they have substantial protection against severe disease,” Barouch said.

Omicron and its subvariants also tend to be less severe than variants like Delta, said Mokdad, who estimates 80 percent of infections with Omicron are actually asymptomatic.

As for the summer, Barouch said he “can’t rule out that there will be a surge,” like there was last summer.

Mokdad said there is “a remote possibility” of a third wave over the summer. But he expects cases to start rising again around the start of October, both because of changing seasons and waning immunity.

Dr. Michael Osterholm, director of the Center for Infectious Disease Research and Policy at the University of Minnesota, said it’s impossible to predict the course of COVID-19.

“Anybody that models this more than a couple of weeks out is basically just using pixie dust,” he said. “There is no pattern whatsoever developing from a seasonality standpoint. It’s all being driven by the variants.”

For Osterholm, variants and subvariants are a “complete wild card” in the epidemiological equation.

“We just have to be humble and acknowledge, we don’t know,” he said.

Mokdad conceded that his expectations for summer and fall are “conditional on not seeing a new variant.”

“This virus is not done with us,” he said. “It’s going to keep infecting, it’s going to keep mutating and we hope that the mutation that’s coming next is less severe, or similar in terms of severity to Omicron. Otherwise, we are in big trouble.”

Though there’s no controlling how the virus might mutate, experts emphasized that behavior still influences an individual’s chance of contracting COVID-19.

Precautions such as masking and distancing remain incredibly important for seniors and immunocompromised individuals, and anyone who interacts with them, since they are still susceptible to severe sickness, said Barouch.

With pandemic restrictions being lifted, it’s important to take a judicious approach and to realize there’s still a substantial amount of virus circulating,” he said. “Even if there is a substantial degree of population immunity and if the risk of severe disease is lower, it’s not zero. People who get infected — even if they’re vaccinated and boosted — still can become quite ill.”


Camille Caldera can be reached at camille.caldera@globe.com.

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Saturday, June 25, 2022

Beijing to reopen schools, Shanghai declares victory over COVID - Reuters.com

People wearing masks walk in a street in Beijing's central business district (CBD) during morning rush hour, following the coronavirus disease (COVID-19) outbreak, in China December 8, 2020. REUTERS/Tingshu Wang/File Photo

SHANGHAI/BEIJING, June 25 (Reuters) - Beijing on Saturday said it would allow primary and secondary schools to resume in-person classes and Shanghai's top party boss declared victory over COVID-19 after the city reported zero new local cases for the first time in two months.

The two major cities were among several places in China that implemented curbs to stop the spread of the Omicron wave during March to May, with Shanghai imposing a two month-long city-wide lockdown that lifted on June 1.

The efforts, part of China's adherence to a zero-COVID policy that aims to eradicate all outbreaks, have brought case numbers down but many of the heavy-handed measures have fuelled anger and even rare protests and taken a heavy toll on the economy.

Beijing shut its schools in early May and asked students to move to online learning amid a spike in locally transmitted COVID cases. Senior year students at middle and high schools were allowed to return to classrooms from June 2.

On Saturday, with case numbers trending lower in recent days, the capital's education commission said all primary and secondary school students in the capital can return to in-person classes from Monday. Kindergartens will be allowed to reopen from July 4.

The Beijing Municipal Bureau of Sports said separately that sports activities for the young can resume at non-school locations on June 27 in areas where no community cases have been reported for seven consecutive days, with the exception of basement venues, which will remain shut.

The Universal Beijing Resort, which had been closed for nearly two months, reopened on Saturday. read more

Meanwhile, Shanghai reported no new local cases - both symptomatic and asymptomatic - for June 24, the first time the Chinese economic hub had done so since Feb. 23.

Shanghai Communist Party chief Li Qiang said at the opening at the city's party congress on Saturday that authorities had "won the war to defend Shanghai" against COVID by implementing the instructions of Chinese President Xi Jinping, and that Beijing's epidemic prevention decisions were "completely correct".

The city, however, remains on edge. Most students have not been allowed to resume in-person classes and dining indoors is still banned. It also plans to continue conducting mass PCR testing for its 25 million residents every weekend until the end of July.

And underscoring continued difficulties in stamping out Omicron, the southern city of Shenzhen, which implemented a week-long lockdown in March, said on Saturday it would shut all cinemas and parks as well as suspend public events in Futian district, after six local cases were discovered there on Friday.

Restaurants in the district, that has a population of around 1.55 million people and houses the headquarters of Chinese insurance giant Ping An and the city government's headquarters, will also be limited to 50% of their usual diner capacity, authorities said.

The city also now requires residents to show a negative COVID-19 test to enter public venues taken within the last 24 hours, shortened from 48 hours previously, which in essence requires people to test daily to enter places such as malls or take public transport.

Reporting by Brenda Goh and Ryan Woo; Additional reporting by David Kirton in Shenzhen; Editing by Edwina Gibbs, Sam Holmes and Michael Perry

Our Standards: The Thomson Reuters Trust Principles.

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Monkeypox mutating more than previously thought, researchers say - Fox News

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There are now more than 200 monkeypox and orthopoxvirus cases confirmed in the U.S., and experts are warning that the virus is mutating more that previously believed.

In a study published Thursday in the journal Nature Medicine, a group of Portuguese researchers found that there were an average of 50 mutations in samples from 2022 compared with those from 2018 and 2019. 

They wrote that the mutation rate – discovered after looking at 15 monekypox virus sequences – may suggest a case of "accelerated evolution."

Genetic analysis from earlier this month previously suggested that there are two distinct strains in the U.S., raising the possibility that the virus had been circulating for a while.

FLORIDA MENINGOCOCCAL OUTBREAK AMONG GAY AND BISEXUAL MEN IS ONE OF THE WORST IN US HISTORY: CDC

Test tube labeled "Monkeypox virus positive" is seen in this illustration taken May 22, 2022. 

Test tube labeled "Monkeypox virus positive" is seen in this illustration taken May 22, 2022.  (REUTERS/Dado Ruvic/Illustration/File Photo/File Photo)

Current data from the Centers for Disease Control and Prevention (CDC) shows the majority of cases in California, New York and Illinois. 

Kentucky health officials announced the state's first probable case on Friday. 

However, scientists have noted that the outbreak is potentially much larger than the current case count.

The CDC confirmed that there has been evidence of local transmission of monkeypox, in addition to the cases where the infected had traveled abroad. 

This 2003 electron microscope image made available by the Centers for Disease Control and Prevention shows mature, oval-shaped monkeypox virions, left, and spherical immature virions, right, obtained from a sample of human skin associated with the 2003 prairie dog outbreak. 

This 2003 electron microscope image made available by the Centers for Disease Control and Prevention shows mature, oval-shaped monkeypox virions, left, and spherical immature virions, right, obtained from a sample of human skin associated with the 2003 prairie dog outbreak.  (Cynthia S. Goldsmith, Russell Regner/CDC via AP)

This weekend is New York City's annual Pride weekend, and some residents told The New York Times they were taking monekypox virus transmission risk into account. 

WHO MEETING ON MONKEYPOX, POSSIBLE GLOBAL HEALTH EMERGENCY

On Thursday health officials in the Big Apple expanded access to a monkeypox vaccine. 

However, citing high demand, the city-run Chelsea Sexual Health Clinic – the only facility in New York administering the vaccine – said it would no longer be able to accommodate walk-ins almost immediately and that all appointments had been filled through next Monday.

The Biden administration has begun to ship monkeypox virus tests to commercial laboratories, which the Department of Health and Human Services (HHS) said would "dramatically expand testing capacity nationwide." 

A section of skin tissue, harvested from a lesion on the skin of a monkey, that had been infected with monkeypox virus, is seen at 50X magnification on day four of rash development in 1968. 

A section of skin tissue, harvested from a lesion on the skin of a monkey, that had been infected with monkeypox virus, is seen at 50X magnification on day four of rash development in 1968.  (CDC/Handout via REUTERS.)

Although the majority of new monkeypox cases have been seen in gay or bisexual men, experts caution that anyone is at potential risk. 

People normally become infected with the monkeypox virus through contact with the skin lesions or bodily fluids of infected animals or humans or through contact with materials contaminated with the virus.

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Monkeypox, which is related to smallpox, has milder symptoms. 

Some symptoms of monkeypox include fever, chills, rash and aches, before lesions develop. 

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