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Tuesday, October 31, 2023

Enhanced tai chi program found to improve cognition, executive function in older adults with mild cognitive impairment - Medical Xpress

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A study of more than 300 older adults experiencing mild cognitive impairment or self-reported memory concerns has found that cognitively enriched tai ji quan, also known as tai chi, was superior to standard tai ji quan or stretching for improving global cognition and reducing walking interference associated with dual tasking.

The authors note that the virtual, home-based exercise program also had and adherence, suggesting that it could be a feasible, acceptable exercise-based therapy for older adults concerned about . The findings are published in Annals of Internal Medicine.

Mild cognitive impairment is characterized by decline in functional cognition and affects 16–20% of people aged older than 65 years. The condition can cause memory and thinking problems and impair dual-task performance, and consequently, interfere with complex tasks of daily living. Both and impaired dual-task performance are associated with a higher risk for falls, increased , and increased mortality. Current clinical guidelines recommend exercise to preserve cognitive function and mitigate decline in , but the effects of cognitively enhanced tai chi are not fully understood.

Researchers from Oregon Research Institute randomly assigned 318 adults with self-reported memory decline and a Clinical Dementia Rating (CDR) global score of 0.5 or lower at baseline to engage in cognitively enhanced tai ji quan, standard tai ji quan, or stretching 1 hour twice weekly for 24 weeks via videoconferencing to compare the effectiveness of the interventions for improving global cognition and reducing dual-task walking costs.

The authors found that cognitively enhanced tai ji quan significantly improved global cognition and lowered cognitive costs associated with dual-task walking at 24 weeks compared with standard tai ji quan or stretching. Favorable improvements were also seen in cognition and function, executive function, and working memory compared with the other two interventions and the effects were sustained at 48 weeks. The intervention was safe, with few mild adverse events reported.

More information: Clinical Effectiveness of Cognitively Enhanced Tai Ji Quan Training on Global Cognition and Dual-Task Performance During Walking in Older Adults With Mild Cognitive Impairment or Self-Reported Memory Concerns, Annals of Internal Medicine (2023). DOI: 10.7326/M23-1603

Citation: Enhanced tai chi program found to improve cognition, executive function in older adults with mild cognitive impairment (2023, October 30) retrieved 1 November 2023 from https://ift.tt/RFn8r4J

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

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Cardiovascular Deaths Due to Extreme Heat Expected To Skyrocket - SciTechDaily

Extreme Heat Cardiology Heart Concept Art

Cardiovascular deaths in the U.S. from extreme heat are projected to double or triple by mid-century if greenhouse gas emissions are not reduced.

In nationwide projections, elderly and black adults are most at risk for cardiovascular death due to extreme heat, finds a new study in the journal, Circulation.

  • Cardiovascular deaths from extreme heat in the United States are projected to increase by 162% by the middle of the century, based on a hypothetical scenario where currently proposed U.S. policies to reduce greenhouse gas emissions have been successfully implemented.
  • A more dire scenario forecasts cardiovascular deaths from extreme heat could increase by 233% in the next 13-47 years if there are only minimal efforts to reduce emissions.
  • The percentage increase in deaths will be greater among elderly people and non-Hispanic black adults in either scenario.

Cardiovascular deaths from extreme heat in the U.S. may more than double by the middle of the century. Without reductions in greenhouse gas emissions, that number could even triple, according to new NIH-funded research published on October 30 in the American Heart Association’s flagship journal Circulation.

“Climate change and its many manifestations will play an increasingly important role on the health of communities around the world in the coming decades, “ said lead study author Sameed Khatana, M.D., M.P.H., assistant professor of medicine at the University of Pennsylvania and a staff cardiologist at the Philadelphia Veterans Affairs Medical Center, both in Philadelphia. “Climate change is also a health equity issue as it will impact certain individuals and populations to a disproportionate degree and may exacerbate preexisting health disparities in the U.S.”

Extreme Heat Cardiology Heart Art Concept

A study published in the American Heart Association’s journal warns that cardiovascular deaths in the U.S. due to extreme heat might double or even triple by mid-century if greenhouse gas emissions continue unchecked. While there are suggestions to introduce infrastructure interventions, like increasing tree cover, more research is required to validate their effectiveness.

Impact of Greenhouse Gas Emissions on Health

How much and how quickly greenhouse gas emissions increase in the next decades will determine the health impacts of extreme heat. More aggressive policies to reduce greenhouse gas emissions have the potential to reduce the number of people who may experience the adverse health effects of extreme heat, according to Khatana.

Previously, the authors examined county-by-county data in the continental U.S. to demonstrate a link between a greater number of extreme heat days and an increase in cardiovascular deaths between 2008-2017. This data served as a benchmark for the analysis in this new study. Researchers used models for future greenhouse gas emissions and future socioeconomic and demographic makeup of the U.S. population to estimate the possible impact of extreme heat on cardiovascular deaths in the middle years of the current century (2036-2065). They estimated the excess number of cardiovascular deaths associated with extreme heat by comparing the predicted number of deaths for each county if no extreme heat occurred vs. if the projected number of heat days occurred.

Key findings include:

  • Between 2008 and 2019, extreme heat was associated with 1,651 excess cardiovascular deaths per year.
  • Even if currently proposed reductions in greenhouse gas emissions are fully implemented, excess cardiovascular deaths due to extreme heat are projected to be 162% higher in the middle of this century compared to the 2008-2019 baseline.
  • However, if those greenhouse gas emissions reduction policies are not implemented, excess cardiovascular deaths due to extreme heat are projected to increase 233% in the coming decades.
  • Depending on how aggressively policies to reduce greenhouse gas emissions are implemented, adults aged 65 and older are projected to have a 2.9 to 3.5 times greater increase in cardiovascular death due to extreme heat in comparison to adults ages 20-64.
  • Non-Hispanic black adults are projected to have a 3.8 to 4.6 times greater increase in cardiovascular death due to extreme heat compared with non-Hispanic white adults, depending on the degree to which greenhouse policies are implemented.
  • Projected increases in deaths due to extreme heat were not significantly different among adults in other racial or ethnic groups, or between men and women.

“The magnitude of the percent increase was surprising. This increase accounts for not only the known association between cardiovascular deaths and extreme heat, but it is also impacted by the population getting older and the proportionate increases in the number of people from other races and/or ethnicities in the U.S.,” Khatana said.

Underlying Factors and Responses

Both medical and environmental factors may influence the greater impact of extreme heat for people in these population groups, he said. Disparities in neighborhood and environmental factors are crucial factors to also consider.

“Previous studies have suggested black residents may have less access to air conditioning; less tree cover; and a higher degree of the ‘urban heat island effect’ — built-up areas having a greater increase in temperature than surrounding less-developed areas,” Khatana said. “Living conditions may also have a role in terms of social isolation, which is experienced by some older adults and has previously been linked with a higher probability of death from extreme heat.”

The findings are unfortunately, not surprising, according to American Heart Association volunteer Robert Brook, M.D., FAHA, who has co-authored several Association scientific statements on air pollution and was not involved in this study.

“Even under the more optimistic moderate scenario of this study, greenhouse gas emissions will increase for some time before tapering down,” said Brook, professor of medicine and executive director of cardiovascular prevention at Wayne State University School of Medicine in Detroit. “Moreover, most of the pollutants persist in the atmosphere for numerous years, and as such, the long-term trend is for significant increases in the frequency of extreme heat events despite near-term actions.

“In conjunction with the growth of more susceptible and vulnerable populations — aging adults and people relocating to warmer locations — heat-related cardiovascular disease deaths are expected to increase over the coming decades. Nevertheless, the study shows that the magnitude of adverse cardiovascular disease effects may be somewhat mitigated by taking earlier action to reduce greenhouse gas emissions that drive climate change.”

While the projections may appear alarming, they are likely conservative, Brook noted.

“The projections of this study focus on cardiovascular disease deaths, and, therefore, they represent conservative estimations of the adverse effects on cardiovascular health due to extreme heat,” he said. “Nonfatal heart attacks, strokes and heart failure hospitalizations outnumber fatal events and are also highly likely to be linked with extreme heat days. The full extent of the public health threat, even just due to cardiovascular death, is likely much greater than presented in this study. “

The projections raise the question of whether infrastructure interventions, such as increasing tree cover in neighborhoods, may lead to improvements in the number of people affected by extreme heat in the U.S. Some research results from Europe suggest that this may be the case, however, studies in the U.S. are lacking.

Brook also noted the role of pollution with excessive heat: “Fine particulate matter air pollution (PM2.5) causes more than 6 million deaths per year. This study adds to the evidence that the full extent of the harmful effects posed by air pollutants extends beyond PM2.5. By substantially increasing extreme heat days, greenhouse air pollutants pose yet further threats to our well-being.”

Study details and background:

  • The researchers compared excess cardiovascular deaths due to extreme heat under two scenarios used by the Intergovernmental Panel on Climate Change, an international body that assesses the science related to climate change caused by human activities. The scenarios were:
  • successful implementation of currently proposed, moderate emission reduction policies so there are lower increases in greenhouse gas emissions; or
  • no significant emission reduction efforts and greenhouse gas emissions continue to increase at the same rate they have over the last two decades.
  • As a baseline, the researchers used county-by-county records from 2008-2019 for deaths during summer months with a primary cause of any cardiovascular condition (including heart attack and stroke), and related data such as the age, sex, race and ethnicity of each person who died and the number of extreme heat days (days with a maximum heat index of 90oF or higher) during the month of the death. The heat index considers both heat and humidity because that reflects how the human body experiences high temperatures, with high humidity interfering with the body’s ability to release heat by sweating.

These results, from data in the continental U.S., may not apply to people living in other regions of the U.S. or the world. The study is also limited by employing two plausible projections of extreme heat and population change, and it is possible that the actual changes in the U.S. may be different.

For more on this study:

Reference: “Projected Change in the Burden of Excess Cardiovascular Deaths Associated With Extreme Heat by Midcentury (2036–2065) in the Contiguous United States” by Sameed Ahmed M. Khatana, Lauren A. Eberly, Ashwin S. Nathan and Peter W. Gro, 30 October 2023, Circulation.
DOI: 10.1161/CIRCULATIONAHA.123.066017

Co-authors and their disclosures are listed in the manuscript. The study was funded by the American Heart Association and the National Heart, Lung, and Blood Institute, a division of the National Institutes of Health.

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Sunday, October 29, 2023

FAST: This acronym could help save a life - WKBN.com

BOARDMAN, Ohio (WKBN) — Sunday is World Stroke Day, and the American Heart Association says it’s important to know the signs, as it can be a matter of life or death.

A stroke can happen to anyone. In fact, the American Heart Association says about 1 in 4 adults over the age of 25 will have a stroke in their lifetime. Doctors say it’s essential everyone knows the most common signs of a stroke. They are known as the fast signs.

F – is for face drooping. Does one side of the face droop, or is it numb? Ask the person to smile. Is the person’s smile uneven?
A – is for arm weakness.
S – is for speech. Is the person having trouble making sense, or slurring their words?
T – is for time to call 911. If you or someone else is experiencing these symptoms, it is an emergency and will require immediate treatment.

“Often other people notice it before the patient notices it themselves. I think it’s critical to identify this early because if you want to treat stroke in the best way possible, you must get the patient immediate medical care,” said Dr. Justin Dunn, cardiologist and AHA volunteer. “This is not something you can say, ‘Let me call my doctor in the morning.'”

Dr. Dunn said there is medication that can help break up the blood clot causing the stroke, or there are medical procedures that can pull the clots out of the brain. These methods are most effective and have the best success when the patient can be seen immediately.

The AHA said strokes can be preventable. They say know the signs and the risk factors. Though anyone can have a stroke, some people are more at risk than others.

Doctors say it’s important to know your numbers, like blood pressure and cholesterol. People with high blood pressure or cholesterol are at a higher risk. Also, those who have diabetes can be at risk.

The AHA says 1 in 4 stroke survivors will have another stroke. Doctors say for most people, making healthy lifestyle choices will keep your chances of having a stroke low.

“The American Heart Association, the American Stroke Association really encourages patients to understand what their risk factors are. Meaning, going to your doctor, knowing what your blood pressure is, know if you have high cholesterol,” Dr. Dunn said. “These things are sometimes things we don’t feel, so we have to be aware that getting them checked frequently and with a physician we trust are very important.”

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Face mask effectiveness: What science knows now - CBS News

When the COVID-19 pandemic took off in 2020, so too did questions over the effectiveness of wearing a face mask to prevent the spread of the virus. Now, three and a half years later, what does the science say?  

In an interview for 60 Minutes, CBS News chief medical correspondent Dr. Jon LaPook posed that question to Linsey Marr, a Virginia Tech University professor specializing in aerosol science.

"They are very helpful in reducing the chances that the person will get COVID because it's reducing the amount of virus that you would inhale from the air around you," Marr said about masks.  

No mask is 100% effective. An N95, for example, is named as such because it is at least 95 percent efficient at blocking airborne particles when used properly. But even if a mask has an 80% efficiency, Marr said, it still offers meaningful protection. 

"That greatly reduces the chance that I'm going to become infected," Marr said. 

Marr said research shows that high-quality masks can block particles that are the same size as those carrying the coronavirus. Masks work, Marr explained, as a filter, not as a sieve. Virus particles must weave around the layers of fibers, and as they do so, they may crash into those fibers and become trapped. 

Marr likened it to running through a forest of trees. Walk slowly, and the surrounding is easy to navigate. But being forced through a forest at a high speed increases the likelihood of running into a tree. 

"Masks, even cloth masks, do something," she said. 

Can contaminated face masks cause infection?

Can contaminated face masks cause infection? 01:11

Early in the pandemic, some guidance from health professionals suggested that wearing a mask might actually lead to infection: A person might encounter a contaminated mask and then touch their eyes, nose, or mouth. But research in the ensuing years has shown that fear to be misplaced. 

"There wasn't any evidence really that that happens," Marr said. 

Marr said her team aerosolized the coronavirus, pulled it through a mask, and then examined how much virus survived on the mask. The study reported some viral particle remained on some cloth masks, but no virus survived on the N95s or surgical masks.

Marr's team also touched artificial skin to masks and looked at how many virus particles transferred to the artificial skin. No infectious virus transferred. 

"I hope the study kind of shows that it's something we don't need to worry about as much as we were told," Marr said.

The videos above were edited by Sarah Shafer Prediger. 

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Scientists Reveal the Right Number of Steps to Walk to Stay Healthy (Hint: It's Not 10K) - Yahoo Life


"Hearst Magazines and Yahoo may earn commission or revenue on some items through these links."

  • The health benefits of walking have been well studied, and range from reducing risk of cardiovascular disease to improving cognition and mood.

  • New research suggests that as little as just under 4,000 steps a day can reduce the risk of dying from all causes.

  • Walking is a great entry into an active lifestyle since it is free and easy, but our fitness experts say to ease into a walking routine slowly and gradually.


Easy and free, walking is one of the best tools for working towards a healthier you. Our bodies are designed to move, and if you're one of the 60% of U.S. adults who doesn't get in the recommended amount of exercise, walking can be a great entry into a more active lifestyle.

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There are many compelling reasons to lace up and get moving. Research has long linked walking and weight loss, as walking effectively increases energy or calorie expenditure over time. Studies have also suggested that walking routinely can reduce the risk of cardiovascular disease, improve a person's cognition and even decrease symptoms of anxiety. But the common guidance of 10,000 steps a day can be unrealistic for many, and new research found that you may be able to reap benefits at a far smaller daily step count.

The meta-analysis, published in the European Journal of Preventive Cardiology, pulled data from seventeen long-term studies with over 226,000 participants across the world. The split was pretty even for male and female, and the average age of the participants was 64 years. The researchers looked at the daily number of step counts and their relationship to all-cause mortality (the risk of dying from all causes) and other factors.

Results showed that walking 3,867 steps daily was enough to begin reducing the risk of dying from any cause — and that just 2,337 steps per day could help reduce the risk of dying from heart disease. The benefits were similar for men and women as well, regardless of where they lived.

But most importantly, the study found that essentially the more you walk, the better – every extra 1,000 steps was associated with a 15% decreased risk of dying from any cause, and a mere extra 500 daily steps was associated with a 7% decrease in dying from heart disease.

How do I start walking after being sedentary?

It's never too late to start a walking program – the study found benefits at every age. But the health benefits were most pronounced for younger individuals under 60 years of age, so starting a walking program early can make a tremendous impact on your overall health.

Our fitness experts recommend starting with about 15-minute walking sessions at a moderate pace for three to five days per week depending on your current fitness level. You can slowly increase the duration and frequency over time, eventually gearing up to 30-minute walking sessions five days a week.

All you will really need to start is a good quality pair of walking shoes – you don't need any additional fancy fitness equipment, which is a major perk.

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How can I increase my daily step count?

An actual walking routine will allow you uninterrupted time to dedicate to staying active. But any amount of walking you do during the day counts towards your daily steps.

If you're having trouble carving out time for your daily walk, try sneaking it into an otherwise busy routine. This is known as non-exercise activity thermogenesis (a.k.a. NEAT) — essentially the energy we expend for everything that is not eating, sleeping or formal exercise (think: walking to work, tending to your yard, even typing).

You can start maximizing your daily NEAT by taking the stairs instead of the elevator and parking farther away from the store, office and restaurant entrances instead of circling the lot for a closer spot. Take a walking meeting while on the phone, or catch up with friends and family over the phone while walking outside. Even forgoing online grocery delivery and going to shop in-person can rack up that daily step count as you peruse the aisles and carry the groceries to the car.

The bottom line: Walking is one of the simplest ways to stay active and get moving. Prior studies have linked a regular walking regimen to reduced risk of heart disease, improved cognition and more. New research shows that you may reap benefits of walking as little as roughly 2,300 steps a day for reducing risk of heart disease and just under 4,000 steps a day to begin reducing the risk of dying from all causes. But additional benefits were seen with an extra 500 to 1,000 steps daily, regardless of age or gender – all the more reason to lace up and get moving!

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Saturday, October 28, 2023

DOH provides weekly flu, COVID-19 updates - KELOLAND.com

SIOUX FALLS, S.D. (KELO) – During the late fall and winter months, the South Dakota Department of Health is publishing weekly updates on the spread of influenza and COVID-19. 

Through Wednesday, Oct. 25, the DOH has reported 25 flu cases and one hospitalization. For COVID-19, the DOH has reported 1,429 cases, 77 hospitalizations and one death from Oct. 1 to Oct. 25. The death was a woman in the 65+ age range.

You can view the flu data and COVID-19 data on the DOH’s dashboards. Weekly updates are published on Wednesdays. 

For the 2022-2023 flu season (Oct. 2022 to Sept. 2023), there was 16,025 cases, 727 hospitalizations and 39 deaths, while the 2022-23 COVID-19 season (Oct. 2022 to Sept. 2023) resulted in 25,606 cases, 1,236 hospitalizations and 192 deaths.

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Syphilis and other STDs are on the rise. States lost millions of dollars to fight and treat them - ABC News

State and local health departments across the U.S found out in June they’d be losing the final two years of a $1 billion investment to strengthen the ranks of people who track and try to prevent sexually transmitted diseases — especially the rapid increase of syphilis cases.

The fallout was quick: Nevada, which saw a 44 percentage-point jump in congenital syphilis from 2021 to 2022, was supposed to get more than $10 million to bolster its STD program budget. Instead, the state’s STD prevention budget went down by more than 75%, reducing its capacity to respond to syphilis, according to Dawn Cribb at the Nevada Division of Public and Behavioral Health.

Several states told The Associated Press that the biggest impact from having the program canceled in the national debt ceiling deal is that they're struggling to expand their disease intervention specialist workforce. These people do contact tracing and outreach, and are a key piece of trying to stop the spread of syphilis, which reached a low point in the U.S. in 2000 but has increased almost every year since. In 2021, there were 176,713 cases — up 31% from the prior year.

“It was devastating, really, because we had worked so hard to shore up our workforce and also implement new activities,” said Sam Burgess, the STD/HIV program director for the Louisiana Department of Health. His state was slated to receive more than $14 million overall, but instead got $8.6 million that must be spent by January 2026. "And we're still scrambling to try to figure out how we can plug some of those funding gaps.”

While men who have sex with men are disproportionately impacted by syphilis, the U.S. Centers for Disease Control and Prevention and health officials across the country also point to the increase in pregnant women who are passing syphilis to their babies. It can cause serious health issues for infants, including blindness and bone damage, or lead to stillbirths. In 2021, there were 77.9 cases of congenital syphilis per 100,000 live births.

Disease intervention specialists often link infected mothers and their partners with care for syphilis, which has mild symptoms for adults, like fever and sores. Doing so in a timely manner can prevent congenital syphilis. The specialists also can help pregnant patients find prenatal care.

“When you have a mother who didn’t know (she had syphilis), it can be very emotional trying to explain ... it could have been prevented if we could have caught it before,” said Deneshun Graves, a public health investigator with the Houston Health Department.

Lupita Thornton, a public health investigator manager in the health department, said she is worried about being able to treat pregnant syphilis patients “before 30 days of delivery, for the baby’s sake.”

The Houston Health Department is in the midst of what it calls a “rapid community outreach response” because of syphilis cases increased by 128% among women from 2019 to 2022, and congenital syphilis cases went from 16 in 2019 to 151 in 2021.

Its STD/HIV bureau was set to receive a total of $10.7 million from the federal grant, but will end up with about 75% of that.

The department has used the money to hire disease intervention specialists and epidemiologists — including Graves. But Thornton said she could use “double of everything," and had planned to bring down the caseload for her investigators by hiring even more people.

It would help Graves, who deals with more than 70 cases at a time.

“You got people that don't want to go in and get treatment. You have people that don't want to answer the phone, so you got to continue to call," Graves said.

Mississippi is also seeing an uptick in congenital syphilis cases, which a recently published study showed rose tenfold between 2016 and 2022. Health officials said a combination of funding shortages and poor access to prenatal care compounds their ability to stop the spread of syphilis.

The Mississippi State Department of Health was supposed to get more than $9 million in federal grant money over five years to expand its disease intervention workforce. Agency head Dr. Dan Edney said one of his top priorities now is finding money from other parts of the state's health budget.

He said the state has been “challenged because of limited state funding” and will need to "cannibalize resources from every program we can so that we can increase our diagnostic rates or treatment rates, and then close the loop with our investigations.”

Arizona has the highest rate of congenital syphilis in the nation: 232.3 cases per 100,000 live births. The federal money helped the state Department of Health Services clear out a backlog of several thousands of non-syphilis STD investigations that had been stalled for years, said Rebecca Scranton, the deputy bureau chief of infectious disease and services.

“We were finally at the point where we were able to breathe again,” Scranton said, “and start really kind of tackling it.”

Scranton acknowledges syphilis will take awhile to fully address, and will look to preserve some of the unspent grant money for what lies ahead.

“You don’t know what challenges are going to come. You know they’re going to come, and you just keep getting creative because our job is really to get services to the folks,” she said. “And that doesn’t change just because you get a funding cut.”

___

The Associated Press Health and Science Department receives support from the Robert Wood Johnson Foundation. The AP is solely responsible for all content.

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Friday, October 27, 2023

'She declined so fast': Parents, doctors warn of RSV as cases increase across San Antonio - KSAT San Antonio

SAN ANTONIO – Taylor Roby Perez said the week her daughter, Isabel, was diagnosed with Respiratory Syncytial Virus (RSV) felt like a rollercoaster.

“She declined so fast,” Roby Perez said. “She went from being super happy and bubbly and smiley to not wanting to eat, not wanting to do anything but be held and sleep.”

RSV is a sickness that doctors say first comes across as mild, cold-like symptoms. But for those at risk, it could cause serious harm.

Doctors in San Antonio say RSV cases are currently on the rise. They say that’s expected with winter approaching.

This week, the CDC issued a health advisory for doctors on what to do now that there is a limited supply of nirsevimab, a monoclonal antibody immunization to help with RSV.

“RSV tends to be a very seasonal disease, especially in South Texas,” said Tarak Patel, a pediatric pulmonologist at Baptist Children’s Hospital.

Patel said the shortage of nirsevimab is in part because of production.

“Partly because it was just recently approved in the manufacture,” Patel said. “It hasn’t had enough time to meet the demand of providing enough of the medication out there for the general public.”

At University Health, Jason Bowling, chief hospital epidemiologist, said RSV cases in the hospital are only going up.

“This past week, actually, we had an increase of about 63% on our hospital’s virology report,” Bowling said. “If you look at the state numbers, it’s going up.”

Bowling said people most at risk for seeing severe cases or complications with RSV are older adults and children under the age of one. He said washing hands and staying away from people who are sick is the best form of protection outside of the vaccines and the antibody. But he said the shortage of the antibody immunization is still hitting University Health.

“This year, we have several things that we didn’t have before for RSV. So there’s two different vaccines, and there’s also a long-acting monoclonal antibody,” Bowling said. “The shortage is actually in this new long-acting monoclonal antibody. We’re no exception. Here, we’re in very short supply. It’s only been given to babies at the very highest risk.”

On Thursday, Roby Perez’s daughter was released from the hospital after a week of care and is now recovering at home.

With her daughter only nine months old, Roby Perez said staying alert of her child’s symptoms and acting early helped her family recover.

“They do get really bad, and they do get really sick, and it’s really fast,” Roby Perez said. “Her personality’s coming back, and she’s starting to laugh again, which was really rough because, for a couple of days, we didn’t see that.”

To learn more about the symptoms of RSV, click here.

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Few Americans Have Gotten the New Covid Shots, C.D.C. Finds - The New York Times

Few Americans have opted to be immunized against the coronavirus so far this fall: Just over 7 percent of adults and 2 percent of children had received a Covid-19 vaccine as of Oct. 14, according to a survey presented on Thursday to scientific advisers to the Centers for Disease Control and Prevention.

The uptake is weak even among those most at risk of severe illness. Only one in five people age 75 or older has been vaccinated, along with about 15 percent of those ages 65 to 74, according to the survey of nearly 15,000 people.

A Walgreens pharmacy sign has a marquee that reads “Covid shots available here” on a sunny day.
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More than 1,200 people are dying of Covid each week, according to C.D.C. data. “That’s a travesty,” said Dr. David Kimberlin, a pediatrician at the University of Alabama at Birmingham who represented the American Academy of Pediatrics at the meeting.

“It’s like an entire neighborhood being wiped out every single week,” Dr. Kimberlin added.

About 16,000 people were hospitalized with Covid in the week ending Oct. 14, compared with nearly 23,000 at the same time last year and more than 44,000 in 2021.

Covid hospitalizations among adults age 75 and older are two to three times as high as among those ages 65 to 74. Rates of hospitalization are highest among Native Americans, Alaska Natives and Black Americans.

Less than 1 percent of Native Americans and Alaska Natives, and 7.6 percent of Black Americans, had received the vaccine as of Oct. 14.

“I’m really disappointed in the low rates of vaccination, because I think it’s a major missed opportunity to improve our overall level of health,” said Dr. Camille Kotton, a physician at Massachusetts General Hospital and an adviser to the C.D.C.

Most people should be able to get the vaccines at no cost through private health insurance, Medicare or Medicaid. Government programs also make the vaccines available for free to children and adults who are underinsured or uninsured, at least through Dec. 31, 2024.

So far, more than 380,000 doses have been administered to uninsured people at more than 24,000 pharmacies.

Still, many people have reported having trouble finding the vaccine at pharmacies, being charged fees or even mistakenly being turned away. At some pharmacies, demand has outstripped supply, leading to canceled appointments.

Dr. Kotton said her clinic and others had received doses of the vaccine only in the past couple of weeks, and she was cautiously optimistic that the immunization rates would pick up.

According to the Health and Human Services Department, 12 million Americans had been vaccinated by Oct. 14. That number grew to 14.8 million in the week after.

About 36 percent of adults age 75 and older in the survey said they would definitely get the shot, while 26 percent said they would probably do so or were still undecided.

Some experts have argued that immunity from previous infections and vaccinations is enough to protect most young people from severe illness and death from Covid.

The C.D.C. recommended on Sept. 12 that all Americans age 6 months and older receive at least one dose of the latest Covid shots. At the time, advisers to the agency were united in endorsing the vaccines for those at high risk because of their age, race or health status.

But a few advisers also expressed concern about recommending the shots to younger people, especially children, and young males at higher risk for myocarditis, an uncommon side effect. Relatively young and healthy people are at much lower risk of severe illness.

Still, in some patients, the virus can inflict long-term damage to the heart and other organs.

About 38 percent of adults in the survey said they would not choose the vaccine for themselves. About the same percentage of parents said they would not have their children immunized.

“We can have the best vaccine in the world, we could have the best ability to access it in the world,” Dr. Kimberlin said, but if 40 percent of people say they don’t want it, he added, “it’s just going to sit on the shelf.”

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Few Americans Have Gotten the New Covid Shots, C.D.C. Finds - The New York Times
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Thursday, October 26, 2023

CDC advisors vote to recommend routine use of the mpox vaccine to protect people at high risk of infection - CNN

CNN  — 

Men who have sex with men and others who are at high risk of mpox infection should get two doses of the Jynneos vaccine, even now that the recent public health emergency in the United States has passed, according to an independent panel of experts that advises the US Centers for Disease Control and Prevention on its vaccine decisions.

CDC’s Advisory Committee on Immunization Practices, or ACIP, voted unanimously on Wednesday to recommend that certain individuals ages 18 and older who are at high risk for getting mpox continue to get the vaccine as a routine part of their sexual health care. Previously, the CDC had recommended vaccination of high-risk individuals during the outbreak.

The recommendations now move to CDC Director Dr. Mandy Cohen, who must sign off.

More than 31,000 Americans were diagnosed with mpox in the 2022-2023 outbreak, including 55 who died, according to CDC data. Most of those who were infected were gay men.

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    According to the CDC, people at high risk for catching mpox include gay, bisexual, and other men who have sex with men, transgender and non-binary people who in the past six months have had at least one of the following: a new diagnosis of at least one sexually transmitted disease; more than one sex partner; sex at a commercial sex venue or in conjunction with a large public event in an area where mpox is spreading; sexual partners of people who have those risks; and people who plan to participate in any of the previous activities.

    More than 2 million people in the United States are eligible for vaccination against mpox under the new recommendations, according to the CDC. To date, approximately 23% of this group has received the recommended two doses of Jynneos.

    Bavarian Nordic, the manufacturer of the vaccine, says it’s preparing for a commercial launch of Jynneos in the United States in the first half of 2024.

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    October 27, 2023 at 02:22AM
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    CDC advisors vote to recommend routine use of the mpox vaccine to protect people at high risk of infection - CNN
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    CDC advisers vote to recommend routine use of the mpox vaccine to protect people at high risk of infection - CNN

    CNN  — 

    Men who have sex with men and others who are at high risk of mpox infection should get two doses of the Jynneos vaccine, even now that the recent public health emergency in the United States has passed, according to an independent panel of experts that advises the US Centers for Disease Control and Prevention on its vaccine decisions.

    CDC’s Advisory Committee on Immunization Practices, or ACIP, voted unanimously on Wednesday to recommend that certain individuals ages 18 and older who are at high risk for getting mpox continue to get the vaccine as a routine part of their sexual health care. Previously, the CDC had recommended vaccination of high-risk individuals during the outbreak.

    The recommendations now move to CDC Director Dr. Mandy Cohen, who must sign off.

    More than 31,000 Americans were diagnosed with mpox in the 2022-2023 outbreak, including 55 who died, according to CDC data. Most of those who were infected were gay men.

    Get CNN Health's weekly newsletter

    Sign up here to get The Results Are In with Dr. Sanjay Gupta every Tuesday from the CNN Health team.

      According to the CDC, people at high risk for catching mpox include gay, bisexual, and other men who have sex with men, transgender and non-binary people who in the past six months have had at least one of the following: a new diagnosis of at least one sexually transmitted disease; more than one sex partner; sex at a commercial sex venue or in conjunction with a large public event in an area where mpox is spreading; sexual partners of people who have those risks; and people who plan to participate in any of the previous activities.

      More than 2 million people in the United States are eligible for vaccination against mpox under the new recommendations, according to the CDC. To date, approximately 23% of this group has received the recommended two doses of Jynneos.

      Bavarian Nordic, the manufacturer of the vaccine, says it’s preparing for a commercial launch of Jynneos in the United States in the first half of 2024.

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      October 27, 2023 at 03:10AM
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      CDC advisers vote to recommend routine use of the mpox vaccine to protect people at high risk of infection - CNN
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      Pfizer, BioNtech say flu-COVID shot generates strong immune response in trial - Reuters

      Oct 26 (Reuters) - Pfizer (PFE.N) and German partner BioNTech said on Thursday that their vaccine to prevent flu and COVID-19 generated a strong immune response against strains of the viruses in an early- to mid-stage trial.

      The companies said they plan to start a late-stage trial in the coming months.

      "This vaccine has the potential to lessen the impact of two respiratory diseases with a single injection and may simplify immunization practices," Annaliesa Anderson, Pfizer's head of vaccine research and development, said in a statement.

      In the trial, the vaccine candidates were compared to a licensed influenza vaccine and the companies' updated COVID-19 vaccine given at the same visit.

      The data from the trial showed that the flu-COVID vaccine demonstrated robust immune responses to influenza A, influenza B and SARS-CoV-2 strains, the companies said.

      (This story has been refiled to fix syntax in the headline)

      Reporting by Manas Mishra in Bengaluru; Editing by Savio D'Souza

      Our Standards: The Thomson Reuters Trust Principles.

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      October 26, 2023 at 10:52PM
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      Pfizer, BioNtech say flu-COVID shot generates strong immune response in trial - Reuters
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      RSV shots are in short supply for babies: See the new CDC guidelines - USA TODAY

      Health officials are reeling back their recommendations about who is eligible for a shot that prevents severe respiratory syncytial virus, or RSV, in infants amid a drug shortage that has coincided with a steady rise in cases.

      In August, an advisory panel recommended the monoclonal antibody shot Beyfortus for all infants under 8 months entering their first RSV season. Children 8 to 19 months who are at increased risk of severe disease also were able to get the shot if they were entering their second season.

      The Centers for Disease Control and Prevention now recommends prioritizing higher doses for babies younger than 6 months and infants who have underlying conditions putting them at risk for severe disease. The agency said parents of children 8 to 19 months should consider getting their babies another monoclonal antibody, palivizumab, if they're eligible.

      One of the drug’s makers, Sanofi, blamed “unprecedented demand” in a statement and vowed to accelerate the production of additional supply along with the company's manufacturing partner AstraZeneca.

      The tightened recommendations came as the CDC reported a spike in RSV cases nationwide. The cases are primarily concentrated in the southeastern U.S., where the agency issued a heath advisory last month. In the U.S., about 58,000 children younger than 5 are hospitalized for RSV each year, and several hundred die of the disease every year.

      COVID vaccineThe new booster appears harder to find. Here's why.

      Before the shortage became apparent, health officials had said babies could get a shot of Beyfortus like a vaccine before the RSV season, which typically runs from fall into winter. Results from clinical trials show the drug prevents RSV lower respiratory tract disease in infants and children entering or during their first RSV season.

      The monoclonal antibody is the first of its kind to be widely available to everyone beyond a small population of immunocompromised children. The other option – palivizumab – is recommended only for high-risk infants born severely premature at 29 weeks or earlier. That drug requires monthly injections.

      Health officials are urging doctors to encourage pregnant patients to get a new vaccine designed to protect newborns from RSV. Babies who receive that drug in utero, don't require followup shots of the antibody vaccine.

      Contributing: The Associated Press

      Follow Adrianna Rodriguez on X, formerly Twitter: @AdriannaUSAT.

      Health and patient safety coverage at USA TODAY is made possible in part by a grant from the Masimo Foundation for Ethics, Innovation and Competition in Healthcare. The Masimo Foundation does not provide editorial input.

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      October 26, 2023 at 04:25PM
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      RSV shots are in short supply for babies: See the new CDC guidelines - USA TODAY
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      Pfizer's combination Covid, flu vaccine will move to final-stage trial after positive data - CNBC

      In this article

      CFOTO | Future Publishing | Getty Images

      Pfizer on Thursday said its combination vaccine candidates targeting Covid and the flu will move to a final-stage trial in the coming months after showing positive initial results in an early to mid-stage study.

      That moves the pharmaceutical giant and its German partner BioNTech one step closer to winning a potential regulatory approval for a combination shot for Covid and the flu. Earlier this year, Pfizer said it hopes to launch a vaccine targeting those two respiratory viruses in 2024 or later.

      Pfizer and other vaccine makers like Moderna and Novavax believe combination shots will simplify the process for people to protect themselves against respiratory viruses that typically surge around the same time of the year.

      "This vaccine has the potential to lessen the impact of two respiratory diseases with a single injection and may simplify immunization practices," Annaliesa Anderson, Pfizer's head of vaccine research and development, said in a release. 

      Pfizer CEO Albert Bourla said during an investor call earlier this month that he believes the convenience offered by combination vaccines will "unlock a significant potential by improving the vaccination rates." 

      Covid vaccine rates in the U.S. were bleak last year, and could look the same this year.

      The trial measured the safety, tolerability and efficacy of Pfizer's combination vaccine candidates among adults ages 18 to 64. The trial also compared the combination vaccines to a licensed influenza vaccine and Pfizer's bivalent Covid shot, which targets the omicron variants BA.4 and BA.5 and the original strain of the virus. 

      The results showed that "lead" formulations of Pfizer's combination vaccine demonstrated robust immune responses to influenza A, influenza B and Covid strains, according to Pfizer. The safety profiles of the combination vaccine candidates were also consistent with the company's Covid vaccine.

      Pfizer and BioNTech are also developing a vaccine that targets both Covid and RSV. Meanwhile, both Moderna and Novavax are developing their own combination shots.

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      Pfizer's combination Covid, flu vaccine will move to final-stage trial after positive data - CNBC
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      Wednesday, October 25, 2023

      What is inflammatory breast cancer? Lesser-known signs to look for beyond lumps - CBS News

      Most adults know lumps are a common breast cancer symptom, but there are other signs to look for that are lesser known and may point to other forms of the disease. 

      "Knowing what both common and uncommon symptoms are, will allow women and men to notify their doctors if there's a change in their breast and to find cancer earlier," Dr. Ashley Pariser, a medical oncologist with Ohio State University Comprehensive Cancer Center, told CBS News.

      A recent survey from the university's cancer center found most people weren't aware of other breast cancer symptoms, including:

      • A retracted, inverted or downward-pointing nipple
      • Breast puckering
      • Loss of feeling
      • Pitting or thickening of the skin
      • Nipple discharge

      These symptoms, which may be a sign of inflammatory breast cancer, can often be mistaken for an infection, Pariser says.

      "If it's not getting better, it's really important to look at an alternative reasons because inflammatory may be one of the reasons," she says.

      Inflammatory breast cancer accounts for only about 1% to 5% of breast cancer cases, according to the American Cancer Society, but it's aggressive and fast growing, making it important to know the warning signs.

      "(Inflammatory breast cancer) doesn't look like a typical breast cancer," the organization's website says. "It often does not cause a breast lump, and it might not show up on a mammogram. This makes it harder to diagnose."

      It says this form of the disease tends to occur more often in younger women, under 40 years of age. It's also more common in Black women compared to White women, and in women who are overweight or obese.

      For Lisa Overholser, things began with pain and swelling in her neck and shoulder in May 2020. 

      "My initial symptoms were some skin changes in my breast," she told CBS News. "It had gotten kind of just thickened and dimpled, but what really drove me to the doctor was pain in my left arm."

      She thought she had a pinched nerve. She was diagnosed instead with stage four inflammatory breast cancer.

      "I quit breathing," she said. "I had worked in physical therapy. I thought, 'Oh, I've got this radiating pain,' never connecting it to the skin changes in my breast."

      Inflammatory breast cancer can be diagnosed after a biopsy or imaging tests such as a mammogram, breast ultrasound or MRI scan, according to the American Cancer Society.

      Overholser's treatment included intensive chemotherapy, surgery, radiation and a two-drug oral treatment to try to keep her disease stable.

      Now she has no active cancer activity and is urging others to talk to their doctor if they notice changes in their body. 

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